Our Cause, Your Impact

Siteman Cancer Center is a pillar of our region and an international leader in cancer treatment, research, and prevention, caring for more than 75,000 patients each year. Every one of these patients has a story—of triumph, strength, and hope for new cures and more effective treatments.  

Each year at Illumination, nearly 500 compassionate donors come together to honor these stories during an evening that blends entertainment and emotion in a special way. As an attendee, you will fuel the work of Siteman’s 600+ research scientists and physicians, supporting the exceptional care of cancer patients today and investing in high-risk, high-reward research that leads to breakthrough treatments and a brighter tomorrow. In fact, the research dollars donated through the Foundation have an exponential impact on the health of our community—for every $1 donated to our Cancer Frontier Fund, Siteman's physician scientists leverage those funds to obtain an additional $13 in federal funding. 

We hope you will join us at the 2026 Illumination to support this beacon of hope for cancer patients and their loved ones.